Kenora OPP re-opened Highway 17A late yesterday afternoon after completing the scene investigation of a fatal accident near Jones Road.
Police said a westbound Dodge Caravan left the road for an undetermined reason yesterday around 8 a.m.
The van struck a rock cut, causing the vehicle to catch fire.
Due to the damage, the four occupants were trapped inside the vehicle.
A 46-year-old female and 19-year-old male were fatally injured in the crash, police said.
An 18-year-old male and 46-year-old male, meanwhile, were transported to Thunder Bay with life-threatening injuries, police added.